Prof. Arnon Ofek

Professor Arnon Ofek serves as deputy director of Sheba Medical Center at Tel Hashomer and is a member of the team that advises Israel's national corona chief

Optimism is fine, but the virus is still here

Israel's vaccination campaign has seen unprecedented success, but questions remain open and new variants could still complicate things.

 

Israel is starting to reap the benefits of its success in fighting the COVID pandemic here. This success is a direct result of the impressive vaccination campaign, which has led to a drop in the number of new cases, the reproduction rate, and the number of COVID patients hospitalized in serious condition, as well as the ongoing reopening of the economy and a return to ordinary life.

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The eyes of the world are on Israel, which is leading in the percentage of citizens vaccinated. Over 5 million people have received at least a first dose, and over 4 million have received both doses – meaning that 57% of the total population in Israel has been vaccinated. There is no doubt that the vaccine is effective, and the data proves it: None of the patients hospitalized and on ECMO machines were vaccinated at all, and only one of the 41 pregnant women hospitalized for COVID was vaccinated. Only 8% of all hospitalized COVID patients received two doses of the vaccine.

Epidemiological studies the Israeli healthcare system has conducted also demonstrate the efficacy of the vaccine. A study by Sheba Medical Center at Tel Hashomer that was published in the prestigious journal Lancet found that the vaccine is 94% effective starting four weeks from the first dose. Another study published by Clalit Health Services published in the New England Journal of Medicine found that vaccinated people were 92% less likely to contract the virus and 94% less likely to develop symptoms if infected. Health Ministry data indicate that the vaccine is capable of reducing COVID mortality by 99%. However, the pandemic has already claimed over 6,000 Israeli lives.

The main message of all these number is that we need to finish vaccinating over 1 million more Israelis, and hope that US clinical studies will soon indicate that children can be safely vaccinated starting at age 12.

As for what comes next, the first most vital step is to fully reinstate the school system. We also need to start working on a system of rapid response to deal with the threat of new variants that could upset everything and force us backward, as has already happened in Italy, which is once again under lockdown because of the British variant.

Any such system needs to be able to provide solutions for enforcement and for testing people who enter Israel through its airports or land crossings. There must be inspectors who check everyone coming into the country and enforce regulations on quarantine, meaning heavy fines for anyone who violates the rules. Another system has to be put in place that will adapt vaccines to any new mutations that might appear. The announcement from Pfizer's CEO that he has instructed the company to develop vaccines for the variants within 100 days is encouraging.

At this stage, issues that remain unanswered have to do with whether or not and to what extent vaccinated individuals can spread the virus, and the possible need to re-vaccinate periodically, as we do every year for the flue. The first question is still being studied, although it is possible to state cautiously that vaccinated people both contract the virus and spread it less than unvaccinated people. As for the second question, Israel has already proven itself unusually capable, and will doubtless be able to run a repeat vaccination campaign if more variants appear, or as the vaccine's efficacy wears off.

Along with the hope and optimism that have seized Israelis, we need to remember that COVID is still with us. We all need to lend our support to the ongoing vaccination campaign and follow regulations as the key to making our way out of the pandemic successfully.

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