A comprehensive 22-year study conducted by Spanish scientists has definitively established that Christopher Columbus, one of history's most celebrated explorers, was a Sephardi Jew from Western Europe. Employing cutting-edge DNA analysis, researchers have finally put to rest a centuries-old enigma surrounding the origins of the man who spearheaded Spanish-funded expeditions from 1490 onward, ultimately leading to European exploration of the Americas.
Columbus's true origins and final resting place have long been subjects of intense debate across multiple countries. Historians have cast doubt on the traditional narrative that he hailed from Genoa, Italy, with alternative theories suggesting Greek, Basque, Portuguese, or British ancestry.

To resolve this mystery, a team led by forensic expert Miguel Lorente examined microscopic samples from remains interred in Seville Cathedral, long designated as Columbus's final resting place despite competing claims. These samples were compared to those of known relatives and descendants, with findings unveiled in a documentary aired on Spain's national channel TVE.
"We have Christopher Columbus's DNA, albeit fragmentary, but sufficient for our purposes. We also have the DNA of Hernando Colón, his son," Lorente explained. "Both the Y chromosome and the mitochondrial DNA of Hernando exhibit characteristics consistent with Jewish ancestry."
Prior to the decree by Catholic monarchs Isabella and Ferdinand ordering Jews to convert or leave Spain, approximately 300,000 Jews called the country home. Many subsequently dispersed across the globe.
After analyzing 25 potential birthplaces, Lorente concluded that Columbus was born in Western Europe. "The investigation was complex due to various factors, including an abundance of data, but the result is almost entirely reliable," he affirmed.
Columbus died in Valladolid, Spain, in 1506, but had wished to be buried on Hispaniola, now shared by the Dominican Republic and Haiti. His remains were transferred there in 1542, moved to Cuba in 1795, and then, as long believed, to Seville in 1898.