Defense Minister Benny Gantz said on Friday he was isolating after testing positive for COVID-19 and was in good health.
"I feel good because I am vaccinated. In the coming days I will manage security affairs from my home," Gantz wrote on Twitter.
Foreign Minister Yair Lapid was confirmed to have been infected with the virus earlier this week, and Finance Minister Avigdor Lieberman contracted COVID last weekend.
According to Yuval Chen, the Knesset officer, United Torah Judaism MK Meir Porush and an advisor to Yisrael Beytenu MK Evgeny Sova have also contracted the virus.
Israel's infection rate stands at 18.36%, according to Health Ministry data released Thursday night. Of the 391,174 people who tested for the virus that day, 65,117 were found to have COVID-19.
There are 412,460 active cases of the virus. There are 593 people in serious condition, 112 of whom are on ventilators.
Although 1,682,867 Israelis have recovered from the disease since the outbreak of the pandemic, 8,370 have died.
Britain's Business Minister Kwasi Kwarteng, meanwhile, told LBC radio Friday: "We should get back to work. We've got to get back to some degree of normality."
"People working in the office do get benefits from working with colleagues, being able to interact directly with them. And I want to get back to a sense that, you know, that the pandemic is turning from a pandemic into an endemic," he said.
"It's something we have to live with. And if we are going to live with it, I think the sooner we get back to the pre-COVID world the better in terms of workplace practices," Kwarteng said.
China, meanwhile, is limiting the torch relay for the Winter Olympics to only three days amid coronavirus worries, organizers said Friday.
Beijing's deputy sports director, Yang Haibin, said safety was the "top priority," with the pandemic, venue preparations, and the possibility of forest fires in Beijing's cold, dry climate all factored in.
The relay will run from Feb. 2-4, taking in the three competition areas of downtown Beijing, the suburb of Yanqing, and Zhangjiakou in the neighboring province of Hebei.
China says only selected spectators will be allowed to attend the events, and Olympic athletes, officials, staff, and journalists are required to stay within a bubble that keeps them from contact with the general public.
Beijing reported its first local omicron infection on Jan. 15, and 11 cases had been confirmed in the capital as of Thursday afternoon, the official Xinhua News Agency reported.
Outside of Beijing, several million people remain under lockdown as part of China's "zero-tolerance" approach to dealing with the pandemic.