The American sanctions imposed on Iran violate the United Nations charter and international law, Malaysian Prime Minister Mahathir Mohamad told a conference in Qatar on Saturday.
"Malaysia does not support the reimposition of the unilateral sanctions by the US against Iran," he told the Doha Forum, also attended by Qatar Emir Tamim bin Hamad Al Thani.
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Malaysia and other countries have lost "a big market" because of the sanctions on Iran, he said.
"Such sanctions clearly violate the United Nations charter and international law; sanctions can only be applied by the United Nations in accordance with the charter," he added.
Mahathir, 94, has for decades been accused of anti-Semitism for his attacks against Jews. In a BBC interview last October, he described Jews as "hook-nosed" and blamed them for the troubles in the Middle East.
In June, Mohamad added to his anti-Semitic record, eliciting laughter from the Cambridge Union – the more than 200-year-old debating and free speech society in Cambridge, England, and the largest society at the University of Cambridge.
"I had some Jewish friends, very good friends. They are not like the other Jews, that's why they are my friends," he said in response to a question about his previous remarks that have been deemed anti-Semitic.
The World Jewish Congress condemned his comments.
In January, the International Paralympic Committee stripped Malaysia of the right to host the 2019 world para-swimming championships after the country banned Israeli athletes from participating.